FAM20C and TAF1D

Data Source:
BioGRID (two hybrid)

		FAM20C	TAF1D
Description		FAM20C golgi associated secretory pathway kinase	TATA-box binding protein associated factor, RNA polymerase I subunit D
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Extracellular Exosome	Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Cytosol Centriolar Satellite Mitotic Spindle
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor Manganese Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Protein Phosphorylation Biomineral Tissue Development Post-translational Protein Modification Cellular Protein Metabolic Process ATP Metabolic Process Enamel Mineralization Odontoblast Differentiation	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases		Raine syndrome; Lethal osteosclerotic bone dysplasia
GWAS		Allergic rhinitis ( 25085501) Alzheimer's disease in APOE e4- carriers ( 25778476)
Interacting Genes		7 interacting genes: FAM118B PFDN1 SMN1 SUV39H2 TAF1D TK1 TSC22D1	24 interacting genes: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP MCPH1 NGEF NHLH2 POLB PTN RPL36AL SMARCB1 TAF1B TMSB4X UBE2D1 UBTF
Entrez ID		56975	79101
HPRD ID		13298	14679
Ensembl ID		ENSG00000177706	ENSG00000166012
Uniprot IDs		Q8IXL6	A0A024R3A9 Q9H5J8
PDB IDs		5YH3
Enriched GO Terms of Interacting Partners?
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