ZYG11B and SH2D2A

		ZYG11B	SH2D2A
Description		zyg-11 family member B, cell cycle regulator	SH2 domain containing 2A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cul2-RING Ubiquitin Ligase Complex	Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding SH3 Domain Binding
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Angiogenesis Signal Transduction Cell Population Proliferation Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway
Pathways			VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494)	Autoimmune thyroid disease ( 32581359) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) SjÃ¶gren's syndrome ( 28076899)
Interacting Genes		4 interacting genes: CUL2 ELOB ELOC GBF1	34 interacting genes: APPL1 AR ARID5A CRK DAPK1 EGFR ERBB2 ERBB3 ERBB4 GAB1 ITK KDR KIT LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MET MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1
Entrez ID		79699	9047
HPRD ID		13356	05152
Ensembl ID		ENSG00000162378	ENSG00000027869
Uniprot IDs		A8DPD7 B4DK95 Q9C0D3	Q5UBZ2 Q5UBZ3 Q9NP31
PDB IDs
Enriched GO Terms of Interacting Partners?
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