ARHGAP10 and SH3BP2

Data Source:
BioGRID (two hybrid)

		ARHGAP10	SH3BP2
Description		Rho GTPase activating protein 10	SH3 domain binding protein 2
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding	Phosphotyrosine Residue Binding Protein Binding SH3 Domain Binding
	Biological Process	Cytoskeleton Organization Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Signal Transduction
Pathways		Rho GTPase cycle Regulation of PAK-2p34 activity by PS-GAP/RHG10
Drugs
Diseases			Cherubism
GWAS		Atrial fibrillation ( 30061737 29892015) Benign childhood epilepsy with centro-temporal spikes ( 32580138) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Immune reponse to smallpox (secreted IL-12p40) ( 22610502) QT interval ( 20031603) Resting heart rate ( 27798624)	Huntington's disease progression ( 28642124) Multiple sclerosis ( 24076602)
Interacting Genes		10 interacting genes: ANKS1A ARF6 CDC42 HRAS PAK2 PKN1 PKN3 RHOA SH3BP2 YWHAQ	31 interacting genes: ABL1 ARHGAP10 CTTN DBNL ERBB2 ERBB3 ERBB4 FGFR1 FLT3 FYN GRB2 HCLS1 KIT LAT LCK MET MYO1F PDLIM7 PLCG1 PLCG2 SH3KBP1 SH3RF1 STAT3 SYK TF TNKS2 VAV1 VAV2 VAV3 YWHAQ ZAP70
Entrez ID		79658	6452
HPRD ID		07949	03657
Ensembl ID		ENSG00000071205	ENSG00000087266
Uniprot IDs		A0A2X0SFB3 A1A4S6	A0A384N6E5 P78314
PDB IDs		2MIO	2CR4 3TWR
Enriched GO Terms of Interacting Partners?
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