CHMP6 and VPS36

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP6	VPS36
Description		charged multivesicular body protein 6	vacuolar protein sorting 36 homolog
Image
GO Annotations	Cellular Component	ESCRT III Complex Multivesicular Body Cytosol Endosome Membrane Membrane Late Endosome Membrane Extracellular Exosome	ESCRT II Complex Nucleus Endosome Cytosol Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein-containing Complex Binding Protein N-terminus Binding	Protein Binding Protein C-terminus Binding Phosphatidylinositol-3-phosphate Binding Ubiquitin Binding
	Biological Process	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Regulation Of Protein Catabolic Process Midbody Abscission Regulation Of Exosomal Secretion ESCRT III Complex Assembly	Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS			Lewy body disease ( 25188341)
Interacting Genes		7 interacting genes: CHMP4A CHMP4B ELOF1 METTL9 SNF8 VPS25 VPS36	7 interacting genes: CHMP6 RILP SNF8 SPRY2 TSG101 UBC VPS25
Entrez ID		79643	51028
HPRD ID		08564	12620
Ensembl ID		ENSG00000176108	ENSG00000136100
Uniprot IDs		Q96FZ7	Q86VN1
PDB IDs		2K3W 3HTU	2HTH 2ZME 3CUQ
Enriched GO Terms of Interacting Partners?
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