ZNF343 and PAX9

Data Source:
BioGRID (two hybrid)

		ZNF343	PAX9
Description		zinc finger protein 343	paired box 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Endoderm Development Odontogenesis Regulation Of Odontogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Face Morphogenesis Cellular Response To Growth Factor Stimulus
Pathways		Generic Transcription Pathway
Drugs
Diseases			Tooth agenesis; Hypodontia
GWAS		Conotruncal heart defects (maternal effects) ( 28468790) Glomerular filtration rate in chronic kidney disease ( 26420894)	Breast cancer ( 29059683 23535729) Height ( 28552196) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Nonsyndromic cleft palate ( 31609978) Prostate cancer ( 29892016)
Interacting Genes		23 interacting genes: ACTN3 APP BFSP2 CCDC125 FAM90A1 JRK KLC4 NEK6 NME7 NUDT22 NXF1 PAX9 RAD51D RUNX1T1 SDCBP STK16 TEPSIN TRIM41 UBQLN1 USP20 ZNF319 ZNF648 ZNF835	26 interacting genes: EYA2 FUBP3 GTF2A1L KDM5B KLF4 KRTAP13-3 LMO2 MSX1 MYLIP NR0B2 PFDN5 PLAGL2 SFN SLAIN1 SSX4 TEPSIN TLE1 TLE2 TLE5 TRIP13 TRIP4 VPS37C WWOX ZNF343 ZNF440 ZNF580
Entrez ID		79175	5083
HPRD ID		18327	01336
Ensembl ID		ENSG00000088876	ENSG00000198807
Uniprot IDs		A0A087WZQ2 Q6P1L6	P55771 Q2L4T1
PDB IDs
Enriched GO Terms of Interacting Partners?
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