PAX9 and PLAGL2

Data Source:
BioGRID (two hybrid)

		PAX9	PLAGL2
Description		paired box 9	PLAG1 like zinc finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Endoderm Development Odontogenesis Regulation Of Odontogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Face Morphogenesis Cellular Response To Growth Factor Stimulus	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Lipid Metabolic Process Post-embryonic Development Chylomicron Assembly Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases		Tooth agenesis; Hypodontia
GWAS		Breast cancer ( 29059683 23535729) Height ( 28552196) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Nonsyndromic cleft palate ( 31609978) Prostate cancer ( 29892016)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)
Interacting Genes		26 interacting genes: EYA2 FUBP3 GTF2A1L KDM5B KLF4 KRTAP13-3 LMO2 MSX1 MYLIP NR0B2 PFDN5 PLAGL2 SFN SLAIN1 SSX4 TEPSIN TLE1 TLE2 TLE5 TRIP13 TRIP4 VPS37C WWOX ZNF343 ZNF440 ZNF580	44 interacting genes: ANKRD11 ARID5A BCAS2 CATSPER1 CCDC120 CTNNA3 DAPP1 DHX57 DVL3 FAM161B FAM83A FAM90A1 GEM GLYCTK GPATCH2L GYS1 INO80B IRX2 KANK2 MAD2L2 MAPK1 MORN4 NOS1AP OIP5 OLIG3 PAX9 PHC2 PIN1 PLAC8 PRR35 RCHY1 RHOBTB3 RIPPLY1 SAMD11 SEPHS1 SMARCD1 TEKT3 TEKT4 TRAF4 TRIM41 VEZF1 YPEL5 ZNF564 ZNF581
Entrez ID		5083	5326
HPRD ID		01336	05333
Ensembl ID		ENSG00000198807	ENSG00000126003
Uniprot IDs		P55771 Q2L4T1	Q9UPG8
PDB IDs
Enriched GO Terms of Interacting Partners?
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