PAX9 and TRIP4

Data Source:
BioGRID (two hybrid)

		PAX9	TRIP4
Description		paired box 9	thyroid hormone receptor interactor 4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Body Neuromuscular Junction Protein-containing Complex Activating Signal Cointegrator 1 Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protease Binding Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Binding Protein Kinase Binding Estrogen Receptor Binding Histone Acetyltransferase Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Endoderm Development Odontogenesis Regulation Of Odontogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Face Morphogenesis Cellular Response To Growth Factor Stimulus	Regulation Of Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Regulation Of Myoblast Differentiation Positive Regulation Of Transcription, DNA-templated Toxin Transport
Pathways
Drugs
Diseases		Tooth agenesis; Hypodontia
GWAS		Breast cancer ( 29059683 23535729) Height ( 28552196) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Nonsyndromic cleft palate ( 31609978) Prostate cancer ( 29892016)	Alzheimer's disease (late onset) ( 24162737) Neuroticism ( 29255261)
Interacting Genes		26 interacting genes: EYA2 FUBP3 GTF2A1L KDM5B KLF4 KRTAP13-3 LMO2 MSX1 MYLIP NR0B2 PFDN5 PLAGL2 SFN SLAIN1 SSX4 TEPSIN TLE1 TLE2 TLE5 TRIP13 TRIP4 VPS37C WWOX ZNF343 ZNF440 ZNF580	23 interacting genes: AR ASCC2 ASCC3 CREBBP EP300 ESR1 ESR2 GTF2A1 JUN NCOA1 NEK6 NFKB1 NR2F2 PAX9 PPARG RARA RELA RXRA SRF TBP THRB UBC XBP1
Entrez ID		5083	9325
HPRD ID		01336	05140
Ensembl ID		ENSG00000198807	ENSG00000103671
Uniprot IDs		P55771 Q2L4T1	Q15650
PDB IDs			2E5O
Enriched GO Terms of Interacting Partners?
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