CENPO and DCDC2

Data Source:
BioGRID (two hybrid)

		CENPO	DCDC2
Description		centromere protein O	doublecortin domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body Mis6-Sim4 Complex	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Microtubule Cilium Axoneme Microtubule Cytoskeleton Cortical Actin Cytoskeleton Centriolar Satellite Kinocilium Mitotic Spindle
	Molecular Function	Protein Binding	Protein Binding Kinesin Binding
	Biological Process	CENP-A Containing Nucleosome Assembly	Neuron Migration Cellular Defense Response Sensory Perception Of Sound Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Smoothened Signaling Pathway Dendrite Morphogenesis Cilium Assembly Regulation Of Cilium Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat mass ( 28552196) Body mass index ( 26426971 29273807) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cognitive function ( 28093568) Coronary artery disease ( 29212778) Height ( 28552196 25282103 23563607) Multiple sclerosis ( 24076602) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Trunk fat mass ( 28552196) Type 1 diabetes ( 21980299)	Airflow obstruction ( 22837378) Estimated glomerular filtration rate ( 31152163 31015462) General cognitive ability ( 29844566) Information processing speed ( 21130836) Uric acid levels ( 21294900)
Interacting Genes		7 interacting genes: CENPP CEP170P1 DCDC2 ERI3 FOS FOSB NECAB2	19 interacting genes: APP B3GNT5 CENPO CKS1B COMMD9 DYNC2LI1 FAM118A KRTAP5-9 KRTAP9-3 LMO3 MICALL2 MRFAP1 NIF3L1 NMU POP5 PTPRCAP SLC38A2 TOLLIP ZNF432
Entrez ID		79172	51473
HPRD ID		14414	09308
Ensembl ID		ENSG00000138092	ENSG00000146038
Uniprot IDs		Q9BU64	Q9UHG0
PDB IDs			2DNF
Enriched GO Terms of Interacting Partners?
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