DCDC2 and CENPO

Data Source:
BioGRID (two hybrid)

		DCDC2	CENPO
Description		doublecortin domain containing 2	centromere protein O
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Microtubule Cilium Axoneme Microtubule Cytoskeleton Cortical Actin Cytoskeleton Centriolar Satellite Kinocilium Mitotic Spindle	Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body Mis6-Sim4 Complex
	Molecular Function	Protein Binding Kinesin Binding	Protein Binding
	Biological Process	Neuron Migration Cellular Defense Response Sensory Perception Of Sound Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Smoothened Signaling Pathway Dendrite Morphogenesis Cilium Assembly Regulation Of Cilium Assembly	CENP-A Containing Nucleosome Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Estimated glomerular filtration rate ( 31152163 31015462) General cognitive ability ( 29844566) Information processing speed ( 21130836) Uric acid levels ( 21294900)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat mass ( 28552196) Body mass index ( 26426971 29273807) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cognitive function ( 28093568) Coronary artery disease ( 29212778) Height ( 28552196 25282103 23563607) Multiple sclerosis ( 24076602) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Trunk fat mass ( 28552196) Type 1 diabetes ( 21980299)
Interacting Genes		19 interacting genes: APP B3GNT5 CENPO CKS1B COMMD9 DYNC2LI1 FAM118A KRTAP5-9 KRTAP9-3 LMO3 MICALL2 MRFAP1 NIF3L1 NMU POP5 PTPRCAP SLC38A2 TOLLIP ZNF432	7 interacting genes: CENPP CEP170P1 DCDC2 ERI3 FOS FOSB NECAB2
Entrez ID		51473	79172
HPRD ID		09308	14414
Ensembl ID		ENSG00000146038	ENSG00000138092
Uniprot IDs		Q9UHG0	Q9BU64
PDB IDs		2DNF
Enriched GO Terms of Interacting Partners?
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