ZBTB25 and KCTD1

Data Source:
BioGRID (two hybrid)

		ZBTB25	KCTD1
Description		zinc finger and BTB domain containing 25	potassium channel tetramerization domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Nucleolus Cytosol Centriolar Satellite Intercellular Bridge
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization
Pathways			Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31015462) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Sudden cardiac arrest ( 21658281)
Interacting Genes		34 interacting genes: APIP COIL CRACR2B CYP2J2 CYSRT1 DDIT3 FCGR3A FHL2 HCLS1 HOMEZ HSBP1 KCTD1 KCTD9 KRTAP10-8 KRTAP17-1 KXD1 LZTS2 MAPK9 MDFI PCBD1 PNMA5 SEPHS1 SORBS3 SSX3 SUMO2 TBC1D5 TNIP1 TRAF2 TRAF6 TSSK3 VCP VMAC ZBTB1 ZBTB2	19 interacting genes: EPM2AIP1 EXOSC1 KCTD15 LMO1 LMO3 LNX1 MORF4L2 NTAQ1 PICK1 POLR1C PRKAA2 PSMA1 SDCBP TGM7 TRAPPC2 TRAPPC2B UBASH3A UBE2I ZBTB25
Entrez ID		7597	284252
HPRD ID		01926	11059
Ensembl ID		ENSG00000089775	ENSG00000134504
Uniprot IDs		G3V2K3 P24278	A0A024RC45 A0A2U3U043 Q719H9
PDB IDs			5BXB 5BXD 6S4L
Enriched GO Terms of Interacting Partners?
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