KCTD1 and TRAPPC2

Data Source:
BioGRID (two hybrid)

		KCTD1	TRAPPC2
Description		potassium channel tetramerization domain containing 1	trafficking protein particle complex subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Centriolar Satellite Intercellular Bridge	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding	Protein Binding Transcription Factor Binding Ion Channel Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization	Skeletal System Development Regulation Of Transcription, DNA-templated Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating
Pathways		Negative regulation of activity of TFAP2 (AP-2) family transcription factors	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Spondyloepiphyseal dysplasia tarda
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31015462) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Sudden cardiac arrest ( 21658281)
Interacting Genes		19 interacting genes: EPM2AIP1 EXOSC1 KCTD15 LMO1 LMO3 LNX1 MORF4L2 NTAQ1 PICK1 POLR1C PRKAA2 PSMA1 SDCBP TGM7 TRAPPC2 TRAPPC2B UBASH3A UBE2I ZBTB25	37 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 JOSD2 KCTD1 LSM3 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBED1 ZBTB38 ZNF438 ZNF655 ZRANB1
Entrez ID		284252	6399
HPRD ID		11059	02189
Ensembl ID		ENSG00000134504	ENSG00000196459
Uniprot IDs		A0A024RC45 A0A2U3U043 Q719H9	P0DI81 P0DI82 Q6IBE5
PDB IDs		5BXB 5BXD 6S4L
Enriched GO Terms of Interacting Partners?
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