KDM6A and AKAP4

Data Source:
BioGRID (affinity chromatography technology)

		KDM6A	AKAP4
Description		lysine demethylase 6A	A-kinase anchoring protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Histone Methyltransferase Complex MLL3/4 Complex	Nucleus Cytoplasm Cytoskeleton CAMP-dependent Protein Kinase Complex Z Disc Motile Cilium Sperm Fibrous Sheath Perinuclear Region Of Cytoplasm Sperm Connecting Piece Sperm Midpiece Sperm Principal Piece Sperm End Piece
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Chromatin DNA Binding Metal Ion Binding Dioxygenase Activity Histone Demethylase Activity (H3-K27 Specific)	Protein Binding Protein Kinase A Binding
	Biological Process	Chromatin Remodeling Heart Development Regulation Of Gene Expression Histone H3-K4 Methylation Histone H3-K27 Demethylation	Signal Transduction Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Single Fertilization Protein Localization Flagellated Sperm Motility Motile Cilium Assembly Establishment Of Protein Localization
Pathways		HDMs demethylate histones Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: GSC2 H3-4 H3C1 H3C14 MEOX2 MTDH NKX2-5 SMAD9 SRF TBX5 TLE1	6 interacting genes: AKAP3 FSIP1 FSIP2 PRKAR1A PRKAR2A PRKAR2B
Entrez ID		7403	8852
HPRD ID		02131	02173
Ensembl ID		ENSG00000147050	ENSG00000147081
Uniprot IDs		A0A087X0R0 A0A6Q8PFK0 B4E0L8 B7ZKN1 B7ZKN5 B7ZKN6 E1U0S6 F5H5V6 F5H6S1 F8W8R6 O15550 Q59HG3 Q86TD1	A0A384MQY7 Q5JQC9
PDB IDs		3AVR 3AVS 6FUK 6FUL
Enriched GO Terms of Interacting Partners?
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