UROD and HMGXB4

Data Source:
BioGRID (two hybrid)

		UROD	HMGXB4
Description		uroporphyrinogen decarboxylase	HMG-box containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	NURF Complex
	Molecular Function	Uroporphyrinogen Decarboxylase Activity Protein Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process	Endosome To Lysosome Transport Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway
Pathways		Heme biosynthesis
Drugs		Coproporphyrin I Coproporphyrinogen III
Diseases		Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS			Hip circumference adjusted for BMI ( 25673412) Platelet count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		10 interacting genes: CHD3 EGFR FAF1 FBXO7 HMGXB4 LRATD2 PHKA2 PILRA TSSK3 VIM	24 interacting genes: AKAP17A CREBBP EPM2A H3-4 HABP4 INO80B JMJD6 LENG8 MX1 NKAPD1 NR1H2 PIAS2 SRPK2 STAC3 STRBP SUMO2 TENT5B TNNT1 TSC22D1 TSPYL2 UBE2I UBL5 UROD ZCCHC10
Entrez ID		7389	10042
HPRD ID		01441	05267
Ensembl ID		ENSG00000126088	ENSG00000100281
Uniprot IDs		P06132	Q7Z641 Q9UGU5
PDB IDs		1JPH 1JPI 1JPK 1R3Q 1R3R 1R3S 1R3T 1R3V 1R3W 1R3Y 1URO 2Q6Z 2Q71 3GVQ 3GVR 3GVV 3GVW 3GW0 3GW3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?