UBE2G2 and RNF157

Data Source:
BioGRID (two hybrid)

		UBE2G2	RNF157
Description		ubiquitin conjugating enzyme E2 G2	ring finger protein 157
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol	Nucleus Cytoplasm Early Endosome Plasma Membrane Cell Body
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity	Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Endosome To Lysosome Transport Protein Ubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Autoubiquitination Positive Regulation Of Dendrite Extension
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083)
Interacting Genes		39 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4	1 interacting genes: UBE2G2
Entrez ID		7327	114804
HPRD ID		04387	15259
Ensembl ID		ENSG00000184787	ENSG00000141576
Uniprot IDs		P60604	Q96PX1
PDB IDs		2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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