TNNI2 and DCAF11

Data Source:
BioGRID (two hybrid)

		TNNI2	DCAF11
Description		troponin I2, fast skeletal type	DDB1 and CUL4 associated factor 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Troponin Complex	Nucleoplasm Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Actin Binding Protein Binding Troponin T Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Contraction	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		Striated Muscle Contraction	Neddylation
Drugs
Diseases		Distal arthrogryposis (DA)
GWAS		Celiac disease ( 23936387) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Inflammatory bowel disease ( 23128233) Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		21 interacting genes: ACTB C1orf109 CALM1 CTNNA3 DCAF11 EFCAB2 ESRRA ESRRG HNF4G MNS1 NME7 PKD2L1 PSMC5 RORB TNNC1 TNNC2 TNNT1 TNNT3 TRIM55 TRIM63 UPF2	13 interacting genes: AGR2 CDKN1A DDB1 GPSM1 NFE2L2 PTEN RCN1 SLBP TNNI1 TNNI2 TNS2 TRIM55 TRIM63
Entrez ID		7136	80344
HPRD ID		01843	18297
Ensembl ID		ENSG00000130598	ENSG00000100897
Uniprot IDs		P48788	B3KSW2 Q59GN6 Q8TEB1
PDB IDs		2MKP
Enriched GO Terms of Interacting Partners?
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