TNNI2 and TNNC2

Data Source:
HPRD (in vitro)

		TNNI2	TNNC2
Description		troponin I2, fast skeletal type	troponin C2, fast skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Troponin Complex	Cytosol Troponin Complex
	Molecular Function	Actin Binding Protein Binding Troponin T Binding	Actin Binding Calcium Ion Binding Protein Binding Calcium-dependent Protein Binding Actin Filament Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Contraction	Skeletal Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs			Felodipine Calcium Octylphenoxy polyethoxyethanol
Diseases		Distal arthrogryposis (DA)
GWAS		Celiac disease ( 23936387) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Inflammatory bowel disease ( 23128233) Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		21 interacting genes: ACTB C1orf109 CALM1 CTNNA3 DCAF11 EFCAB2 ESRRA ESRRG HNF4G MNS1 NME7 PKD2L1 PSMC5 RORB TNNC1 TNNC2 TNNT1 TNNT3 TRIM55 TRIM63 UPF2	4 interacting genes: PIK3R3 TBC1D1 TNNI2 TNNI3
Entrez ID		7136	7125
HPRD ID		01843	08929
Ensembl ID		ENSG00000130598	ENSG00000101470
Uniprot IDs		P48788	C9J7T9 P02585
PDB IDs		2MKP
Enriched GO Terms of Interacting Partners?
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