TSPAN4 and FCHO1

Data Source:
BioGRID (two hybrid)

		TSPAN4	FCHO1
Description		tetraspanin 4	FCH and mu domain containing endocytic adaptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Vesicle	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle
	Molecular Function	Antigen Binding Integrin Binding Protein Binding	Protein Binding AP-2 Adaptor Complex Binding
	Biological Process	Protein-containing Complex Assembly	Clathrin Coat Assembly Membrane Organization Clathrin-dependent Endocytosis
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Falling risk ( 32999390)	Basophil count ( 32888494) Coronary artery disease ( 29212778) Monocyte percentage of white cells ( 32888494)
Interacting Genes		49 interacting genes: CATSPER1 CD46 CD81 CD9 CHRD CLDN11 CLEC2D CREB3 CREB5 CYSRT1 EVA1A FCHO1 FRS3 GNE GRN GUCD1 HOXA1 ITGA3 ITGA6 ITGB1 KRTAP10-1 KRTAP10-8 KRTAP4-11 KRTAP4-5 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE2B LCE2D LCE3A LCE3C LCE3D LCE4A LRRC25 LTB4R2 MDFI MGAT5B MKRN3 NBPF19 NOTCH2NLA NR4A3 OTX1 PHLDA1 PLSCR4 SGPL1 TEKT4 TMEM106A VGLL3	51 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688
Entrez ID		7106	23149
HPRD ID		04033	16887
Ensembl ID		ENSG00000214063	ENSG00000130475
Uniprot IDs		A0A024RCE1 A8MVV6 O14817	A0A0C3SFZ9 B7ZAZ3 O14526
PDB IDs
Enriched GO Terms of Interacting Partners?
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