FCHO1 and PRPH

Data Source:
BioGRID (two hybrid)

		FCHO1	PRPH
Description		FCH and mu domain containing endocytic adaptor 1	peripherin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle	Cytoplasm Intermediate Filament Membrane Axon Perikaryon Type III Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding AP-2 Adaptor Complex Binding	Structural Molecule Activity Protein Binding
	Biological Process	Clathrin Coat Assembly Membrane Organization Clathrin-dependent Endocytosis	Intermediate Filament Cytoskeleton Organization
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases			Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS		Basophil count ( 32888494) Coronary artery disease ( 29212778) Monocyte percentage of white cells ( 32888494)	Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)
Interacting Genes		51 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688	36 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT19 KRT20 KRT24 KRT27 KRT31 KRT75 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572
Entrez ID		23149	5630
HPRD ID		16887	01365
Ensembl ID		ENSG00000130475	ENSG00000135406
Uniprot IDs		A0A0C3SFZ9 B7ZAZ3 O14526	B3KWQ6 P41219
PDB IDs
Enriched GO Terms of Interacting Partners?
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