FCHO1 and TCEA2

Data Source:
BioGRID (two hybrid)

		FCHO1	TCEA2
Description		FCH and mu domain containing endocytic adaptor 1	transcription elongation factor A2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle	Nucleoplasm Centrosome Transcription Elongation Factor Complex
	Molecular Function	Protein Binding AP-2 Adaptor Complex Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Clathrin Coat Assembly Membrane Organization Clathrin-dependent Endocytosis	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Basophil count ( 32888494) Coronary artery disease ( 29212778) Monocyte percentage of white cells ( 32888494)	Adult body size ( 32376654) Adventurousness ( 30643258) Anxiety ( 31906708) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Eosinophil counts ( 32888494) Low density lipoprotein cholesterol levels ( 32154731) Pulse pressure ( 27841878 30578418) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969)
Interacting Genes		51 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688	133 interacting genes: ADAMTSL4 AGR2 AGTRAP AKT1S1 ALAS1 AMOTL2 APP ARMC10 AXIN2 BACH2 BHLHB9 BICD2 BOLL BRCA1 BTBD6 CAMKV CBY2 CCDC136 CCDC157 CCSER2 CDK11B CENPT CEP44 CEP76 CMTM4 CMTM6 CNTROB COX20 CYSRT1 DAB1 DCAF10 DES DHRS2 DNAJB9 DVL3 EAF1 EAF2 ERBB3 EXOSC8 FADD FAM9B FBF1 FCHO1 FXR1 GAS8 GIGYF1 GOLGA2 GPKOW GRIPAP1 GTF2B HES7 HIGD1C HIP1 HMBOX1 HOMEZ HSF2BP IKZF1 IKZF4 KCNF1 KCTD10 KCTD7 KIAA1958 KRT40 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP5-9 KXD1 LIMS1 LMNA LRRK2 LZTS1 LZTS2 MAGEA11 MARK3 MCC MCM2 MDK MEOX2 MID2 MKRN3 MSANTD4 MTUS2 NAB2 NECAB1 NECAB2 OSBPL3 PIBF1 PICK1 PIH1D2 PNMA1 PNMA5 POU6F2 PRPH RBPMS RETREG3 RPA1 SCYL1 SH3GL2 SSC5D STAC3 STX11 SYNE4 TARBP2 TAX1BP1 TAX1BP3 TBC1D1 TCF4 TEPSIN TFCP2 THAP1 TMEM71 TNIP1 TOX2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM38 TRIM41 TRIM54 TSGA10 USP54 VIM WDR47 ZBTB22 ZBTB43 ZBTB8A ZBTB9 ZKSCAN8 ZNF526 ZRANB1
Entrez ID		23149	6919
HPRD ID		16887	16069
Ensembl ID		ENSG00000130475	ENSG00000171703
Uniprot IDs		A0A0C3SFZ9 B7ZAZ3 O14526	Q15560 Q6IB64
PDB IDs			2LW4
Enriched GO Terms of Interacting Partners?
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