THOP1 and PALS2

		THOP1	PALS2
Description		thimet oligopeptidase 1	protein associated with LIN7 2, MAGUK family member
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Intermembrane Space Cytosol	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Metalloendopeptidase Activity Protein Binding Peptide Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Polyubiquitination Proteolysis Peptide Metabolic Process	Protein-containing Complex Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Platelet count ( 32888494) Plateletcrit ( 32888494) Total cholesterol levels ( 28334899)
Interacting Genes		9 interacting genes: AGTR1 CALM1 EPN2 LINC01554 MPHOSPH6 PALS2 PRKACA STK11 TRAF2	30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1
Entrez ID		7064	51678
HPRD ID		03072	09509
Ensembl ID		ENSG00000172009	ENSG00000105926
Uniprot IDs		P52888	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs		1S4B 2O36
Enriched GO Terms of Interacting Partners?
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