PALS2 and LIN7A

Data Source:
HPRD (in vivo, in vitro)

		PALS2	LIN7A
Description		protein associated with LIN7 2, MAGUK family member	lin-7 homolog A, crumbs cell polarity complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse Extracellular Exosome MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane
	Molecular Function	Protein Binding	Protein Binding L27 Domain Binding
	Biological Process	Protein-containing Complex Assembly	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Synaptic Vesicle Transport Inner Ear Development Protein-containing Complex Assembly Protein Localization To Basolateral Plasma Membrane
Pathways			Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS			Age-related cataracts (age at onset) ( 25352737) Dental caries ( 23259602)
Interacting Genes		30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1	24 interacting genes: ABCA1 ADGRB1 APP BAIAP2 CASK CHRD DLG2 DLG3 DLG4 DNAJC5 ECM1 FAM9B GOLGA2 GRIN2B KCNJ12 MDFI MPP2 MPP3 MPP7 NOTCH2NLA PALS1 PALS2 SLC6A12 ZYX
Entrez ID		51678	8825
HPRD ID		09509	04542
Ensembl ID		ENSG00000105926	ENSG00000111052
Uniprot IDs		A0A024RA25 B8ZZG1 Q9NZW5	O14910
PDB IDs
Enriched GO Terms of Interacting Partners?
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