PALS2 and EIF3G

Data Source:
HPRD (two hybrid)

		PALS2	EIF3G
Description		protein associated with LIN7 2, MAGUK family member	eukaryotic translation initiation factor 3 subunit G
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Protein-containing Complex Assembly	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Viral Translational Termination-reinitiation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Interacting Genes		30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1	28 interacting genes: ACD AIFM1 APP EIF3A EIF3B EIF3C EIF3D EIF3H EIF3K EIF5 EPB41 FAM9B GADD45G GOLGA2 LMNA MEOX2 METTL3 MIF4GD MPHOSPH6 PALS2 PIN1 PKN2 POT1 PRKAG1 SMN1 SNCA TK1 TRIM14
Entrez ID		51678	8666
HPRD ID		09509	04886
Ensembl ID		ENSG00000105926	ENSG00000130811
Uniprot IDs		A0A024RA25 B8ZZG1 Q9NZW5	O75821
PDB IDs			2CQ0 2MJC 5K0Y 6YBS 6ZMW
Enriched GO Terms of Interacting Partners?
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