TAF12 and TAF8

Data Source:
HPRD (in vitro, in vivo)

		TAF12	TAF8
Description		TATA-box binding protein associated factor 12	TATA-box binding protein associated factor 8
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GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation SnRNA Transcription By RNA Polymerase II Regulation Of Fat Cell Differentiation Maintenance Of Protein Location In Nucleus
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Type 2 diabetes ( 31049640)	Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		23 interacting genes: ATF7 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	13 interacting genes: H3-4 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9
Entrez ID		6883	129685
HPRD ID		15981	18167
Ensembl ID		ENSG00000120656	ENSG00000137413
Uniprot IDs		Q16514	Q7Z7C8
PDB IDs		1H3O 6MZC 6MZD 6MZL 6MZM	4WV4 4WV6 5FUR 6MZC 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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