TAF12 and TAF2

Data Source:
HPRD (in vitro, in vivo)

		TAF12	TAF2
Description		TATA-box binding protein associated factor 12	TATA-box binding protein associated factor 2
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GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator	G2/M Transition Of Mitotic Cell Cycle Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Response To Organic Cyclic Compound Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Type 2 diabetes ( 31049640)	Heart rate response to exercise ( 29769521)
Interacting Genes		23 interacting genes: ATF7 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	14 interacting genes: ESR1 H3-4 PUF60 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9
Entrez ID		6883	6873
HPRD ID		15981	07060
Ensembl ID		ENSG00000120656	ENSG00000064313
Uniprot IDs		Q16514	A0A024R9E6 B3KMD8 Q6P1X5
PDB IDs		1H3O 6MZC 6MZD 6MZL 6MZM	5FUR 6MZC 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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