TAF8 and TAF12

Data Source:
HPRD (in vitro, in vivo)

		TAF8	TAF12
Description		TATA-box binding protein associated factor 8	TATA-box binding protein associated factor 12
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Perinuclear Region Of Cytoplasm	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation SnRNA Transcription By RNA Polymerase II Regulation Of Fat Cell Differentiation Maintenance Of Protein Location In Nucleus	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)	Type 2 diabetes ( 31049640)
Interacting Genes		13 interacting genes: H3-4 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9	23 interacting genes: ATF7 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		129685	6883
HPRD ID		18167	15981
Ensembl ID		ENSG00000137413	ENSG00000120656
Uniprot IDs		Q7Z7C8	Q16514
PDB IDs		4WV4 4WV6 5FUR 6MZC 6MZL 6MZM	1H3O 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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