SPAST and IST1

  • Data Source:
  • BioGRID (affinity chromatography technology, two hybrid, pull down)

SPAST

IST1

Description spastin IST1 factor associated with ESCRT-III
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Bisphosphonate-associated atypical femoral fracture ( 31006051)
  • Inflammatory biomarkers ( 24182552)
  • Interleukin-18 levels ( 31584380)
  • Male-pattern baldness ( 28196072)
  • Apolipoprotein B levels ( 32203549)
  • Blood protein levels ( 28240269)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Intelligence (MTAG) ( 29326435)
  • Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
Interacting Genes 4 interacting genes: CHMP1B IST1 RTN1 SSNA1 9 interacting genes: APEH ATXN1 BAG4 CAPN7 CHMP1A SPAST TOX3 UBQLN1 UBQLN2
Entrez ID 6683 9798
HPRD ID 05044 13784
Ensembl ID ENSG00000021574 ENSG00000182149
Uniprot IDs E5KRP5 E5KRP6 Q9UBP0 B4DXC9 P53990
PDB IDs 3EAB 3VFD 5Z6Q 5Z6R 6PEK 6PEN 3FRR 3FRS 3JC1 4U7E 4U7I 4U7Y 4WZX 6E8G 6TZ4 6TZ5 6TZA
Enriched GO Terms of Interacting Partners?
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