SOX10 and HIVEP1

Data Source:
HPRD (two hybrid)

		SOX10	HIVEP1
Description		SRY-box transcription factor 10	HIVEP zinc finger 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Extrinsic Component Of Mitochondrial Outer Membrane	Nucleus Nucleoplasm Mitochondrion Cytosol Nuclear Body
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding Promoter-specific Chromatin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Neural Crest Cell Migration Morphogenesis Of An Epithelium Positive Regulation Of Neuroblast Proliferation Regulation Of Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Peripheral Nervous System Development Anatomical Structure Morphogenesis Negative Regulation Of Schwann Cell Proliferation Oligodendrocyte Development Positive Regulation Of Gliogenesis Central Nervous System Myelination Melanocyte Differentiation Positive Regulation Of Myelination Lacrimal Gland Development Cellular Response To Drug Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cell Maturation Enteric Nervous System Development Digestive Tract Morphogenesis Developmental Growth Oligodendrocyte Differentiation Morphogenesis Of A Branching Epithelium Cellular Response To Progesterone Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II BMP Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases		46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis Waardenburg syndrome (WS)
GWAS		Mean spheric corpuscular volume ( 32888494)	Adult body size ( 32376654) Alcohol and nicotine co-dependence ( 22488850) Asthma ( 32296059) Body mass index ( 28892062 25673413 29273807) Chronotype ( 30696823) Feeling worry ( 29500382) Figural/spatial cognitive ability ( 31620175) General risk tolerance (MTAG) ( 30643258) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 32888494) Takayasu arteritis ( 25604533)
Interacting Genes		35 interacting genes: ALX4 C10orf55 CDK6 CEBPA CRX DAZAP2 DLX5 EGR2 EXOC5 GSK3B HHEX HIVEP1 HOXA3 HOXC4 HSF4 JUN MAGED1 MEOX1 NMI OLIG2 PAX3 PAX6 POU3F2 POU3F3 POU5F1 POU6F2 PRRX1 PRRX2 SP1 SUMO1 SUMO2 SUMO3 TCF12 UBE2I UTF1	70 interacting genes: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BANP BHLHE40 BNIP3 BRCA1 CACNA1A CCNK CDC37 CLK1 CREB1 DNAJA1 ELOA EMG1 FAM104B GAA GSDMB HPD HSPA1A IGFN1 IMMT KDF1 MAGED1 MAPK14 MAPK8 MIEN1 MTMR3 NFYC NHLH1 NINJ1 NRF1 NUCB1 OGT OTX1 PLEKHB2 POGZ POU2F1 POU6F2 PRKAR1A PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RAB1A RBM47 RBPMS RIDA RNF186 ROR2 SDCBP SERTAD1 SH3KBP1 SMAD3 SNX4 SOCS3 SOX10 SP4 SRPK2 STAT3 TENT5B TMEM176A VEZF1 ZC3H10 ZFHX3
Entrez ID		6663	3096
HPRD ID		03752	01925
Ensembl ID		ENSG00000100146	ENSG00000095951
Uniprot IDs		A0A024R1N6 P56693	P15822
PDB IDs			1BBO 3ZNF 4ZNF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?