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SLIT1 and ZNF620
Data Source:
BioGRID
(two hybrid)
SLIT1
ZNF620
Description
slit guidance ligand 1
zinc finger protein 620
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Molecular Function
Calcium Ion Binding
Protein Binding
Heparin Binding
Roundabout Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Biological Process
Nuclear Migration
Axon Guidance
Motor Neuron Axon Guidance
Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration
Retinal Ganglion Cell Axon Guidance
Dorsal/ventral Axon Guidance
Axon Extension Involved In Axon Guidance
Forebrain Morphogenesis
Negative Chemotaxis
Negative Regulation Of Synapse Assembly
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Pathways
Netrin-1 signaling
Signaling by ROBO receptors
Regulation of commissural axon pathfinding by SLIT and ROBO
Regulation of cortical dendrite branching
Regulation of expression of SLITs and ROBOs
Generic Transcription Pathway
Drugs
Diseases
GWAS
Bipolar disorder (
28115744
)
Diastolic blood pressure (alcohol consumption interaction) (
24376456
)
Mean arterial pressure (alcohol consumption interaction) (
24376456
)
Obesity-related traits (
23251661
)
Neuroticism (
29255261
)
Interacting Genes
16 interacting genes:
ADAMTSL4
ATN1
CHRDL2
CYSRT1
FHL5
GPC1
HOXA1
KRTAP1-1
KRTAP10-8
KRTAP13-2
KRTAP13-3
MEOX2
MTNR1A
ROBO1
TRIM42
ZNF620
72 interacting genes:
ABLIM3
ATG9A
BFSP2
BOLA2
BOLA2B
C1orf216
C22orf39
CABP5
CARD9
CCDC102B
CCDC6
CCHCR1
CCNC
CDCA7L
CDKN2D
CHAF1A
CIB3
CINP
CLIC3
CTNNA3
DGCR6L
DTX2
EAF1
EEF2KMT
EIF4A2
EPM2AIP1
EXOSC5
FHL2
GAS8
GLYCTK
GRB2
GYS1
IGFN1
IL16
JRK
KCTD9
LMO1
LMO3
MAGOHB
MAP2K5
METTL21A
MFAP1
MISP
MLX
MYOZ3
NDOR1
NME7
NOXA1
OAZ3
PIBF1
PIK3R3
PLOD3
POLE2
RIPPLY1
RUSC1
SAAL1
SART3
SLIT1
SNAPC3
TENT5B
TPM2
TRAF4
TRIM10
TRIM50
TSEN15
TSR2
USP20
ZBTB16
ZFHX3
ZIC1
ZNF24
ZNF648
Entrez ID
6585
253639
HPRD ID
04773
15878
Ensembl ID
ENSG00000187122
ENSG00000177842
Uniprot IDs
A6H8V1
O75093
Q6ZNG0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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