TMEM237 and GPR25

Data Source:
BioGRID (two hybrid)

		TMEM237	GPR25
Description		transmembrane protein 237	G protein-coupled receptor 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane Photoreceptor Connecting Cilium Ciliary Transition Zone Cone Photoreceptor Outer Segment Rod Photoreceptor Outer Segment	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Regulation Of Wnt Signaling Pathway Cilium Assembly	G Protein-coupled Receptor Signaling Pathway
Pathways			G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)
Interacting Genes		122 interacting genes: ABHD16A ADAM33 ADIPOQ APOD APOL3 AQP1 ATP13A1 BET1 BLCAP BNIP2 BTN2A2 C1GALT1 C3orf52 C4orf3 CBLIF CCDC167 CD53 CDS1 CFHR5 CLDN4 CLN6 CNIH3 CTSA CXCL16 CXCL9 CYB5B EFNA5 EMC6 ERMP1 EXTL1 FBXO7 FKBP14 FXYD6 FZD7 GJB2 GKN2 GPR152 GPR25 GPR42 GRM2 GUCA2A GYPA IER3IP1 IFNGR1 IGFBP5 INSIG1 INSIG2 JAGN1 LAT LEPROTL1 LPAR3 LRP10 LTA MFF MFSD5 MFSD6 MS4A13 OPRD1 ORMDL3 OTOP2 OTOP3 PLPPR2 PNLIPRP1 POMGNT1 PRB1 PRNP RETREG3 RHD ROBO2 RPRM RUSF1 SEC22A SERP2 SERPINE1 SFXN5 SLC12A7 SLC16A4 SLC29A2 SLC2A5 SLC30A8 SLC35A4 SLC35B2 SLC35B4 SLC35E4 SLC35G1 SLC38A2 SLC38A7 SLC39A2 SLC39A9 SLC41A1 SLC41A2 SLC52A1 SLC5A4 SLC7A1 SLC7A3 ST6GAL2 STRIT1 STX8 TLCD4 TM4SF19 TM6SF2 TMEFF2 TMEM107 TMEM11 TMEM128 TMEM144 TMEM147 TMEM179B TMEM201 TMEM254 TMEM42 TMEM60 TMEM72 TMEM86B TRARG1 UNC93A UNC93B1 UPK1B VAMP3 VEGFA YIPF6 ZFPL1	32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB
Entrez ID		65062	2848
HPRD ID		12448	03707
Ensembl ID		ENSG00000155755	ENSG00000170128
Uniprot IDs		Q96Q45	O00155
PDB IDs
Enriched GO Terms of Interacting Partners?
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