SIM1 and ARNT

  • Data Source:
  • HPRD (in vivo, in vitro, two hybrid)

SIM1

ARNT

Description SIM bHLH transcription factor 1 aryl hydrocarbon receptor nuclear translocator
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body size at age 10 ( 32376654)
  • Creatinine levels ( 29403010)
  • Erectile dysfunction ( 30297428)
  • Estimated glomerular filtration rate ( 31152163)
  • Gait speed in old age ( 28077804)
  • Glomerular filtration rate ( 29403010)
  • Iris color (L* coordinate) ( 30895295)
  • Irritable mood ( 29500382)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Major depressive disorder ( 27479909)
  • Menarche (age at onset) ( 25231870)
  • Neurociticism ( 29500382)
  • Neuroticism ( 29255261)
  • Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
Interacting Genes 3 interacting genes: ARNT ARNT2 HSP90AA1 77 interacting genes: ADH5 AHR AHRR AIP AKT1 ARL14 ARNT2 BECN1 BRCA1 CALCOCO1 CASP3 CASP9 CCND2 CCNE1 CD44 CDK4 CDK6 CDKN2A CDKN2B CDKN2C CSNK2A1 DIABLO EP300 EPAS1 EPHA2 ERBB2 ESR1 FGFR4 FZR1 GLIS1 GLIS2 GMNN GTF2F1 GTF2F2 HEY1 HEY2 HGF HIF1A HIF3A HNF4A IRAK4 KPNA1 KPNA3 KPNA5 KPNA6 LATS2 LSM8 MAP2K5 MAPK14 MTA3 MYC NCOA1 NCOA2 NCOA7 NCOR2 NF2 NPAS4 PDGFRA PML PTGES3 RAF1 RELA SENP6 SIM1 SIM2 SMAD9 SP1 STK11 STRBP TACC3 TEAD2 TGM2 TNFAIP1 TP53 TRIP11 TUBB2A UBE2I
Entrez ID 6492 405
HPRD ID 07049 00524
Ensembl ID ENSG00000112246 ENSG00000143437
Uniprot IDs P81133 A8K6P0 B0AZM1 P27540 Q53F30
PDB IDs 1D7G 1X0O 2A24 2ARN 2B02 2HV1 2K7S 3F1N 3F1O 3F1P 3H7W 3H82 4EQ1 4GHI 4GS9 4H6J 4LPZ 4PKY 4XT2 5TBM 5UFP 5V0L 6CZW 6D09 6D0B 6D0C
Enriched GO Terms of Interacting Partners?
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