SIM1

Description		SIM bHLH transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Nervous System Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Creatinine levels ( 29403010) Erectile dysfunction ( 30297428) Estimated glomerular filtration rate ( 31152163) Gait speed in old age ( 28077804) Glomerular filtration rate ( 29403010) Iris color (L* coordinate) ( 30895295) Irritable mood ( 29500382) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Major depressive disorder ( 27479909) Menarche (age at onset) ( 25231870) Neurociticism ( 29500382) Neuroticism ( 29255261) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
Novel Interacting Genes		1 novel interacting genes: FOXO3
Interacting Genes		3 interacting genes: ARNT ARNT2 HSP90AA1
Entrez ID		6492
HPRD ID		07049
Ensembl ID		ENSG00000112246
Uniprot IDs		P81133
PDB IDs
Enriched GO Terms of Interacting Partners?
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