PORCN and CBARP

Data Source:
BioGRID (two hybrid)

		PORCN	CBARP
Description		porcupine O-acyltransferase	CACN subunit beta associated regulatory protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane AMPA Glutamate Receptor Complex Glutamatergic Synapse	Plasma Membrane Integral Component Of Membrane Secretory Granule Growth Cone Synaptic Vesicle Membrane
	Molecular Function	Transferase Activity, Transferring Acyl Groups Wnt-protein Binding Palmitoleoyltransferase Activity	Ion Channel Binding
	Biological Process	Protein Lipidation Glycoprotein Metabolic Process Wnt Signaling Pathway Protein Palmitoylation Lipid Modification Protein Palmitoleylation Canonical Wnt Signaling Pathway Wnt Protein Secretion Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels	Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Calcium Ion Transmembrane Transport
Pathways		WNT ligand biogenesis and trafficking LGK974 inhibits PORCN
Drugs
Diseases		Focal dermal hypoplasia; Goltz-Gorlin syndrome
GWAS
Interacting Genes		9 interacting genes: APOC2 APOC4 CBARP WNT1 WNT3A WNT4 WNT5B WNT6 WNT7B	10 interacting genes: ABHD16A ATP13A1 CALHM6 MFSD5 MS4A13 NCK2 PORCN SLC35F6 SLC39A9 TRAF3IP3
Entrez ID		64840	255057
HPRD ID		06680	16627
Ensembl ID		ENSG00000102312	ENSG00000099625
Uniprot IDs		Q9H237	Q8N350
PDB IDs
Enriched GO Terms of Interacting Partners?
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