SH3GL1 and B3GAT1

Data Source:
BioGRID (two hybrid)

		SH3GL1	B3GAT1
Description		SH3 domain containing GRB2 like 1, endophilin A2	beta-1,3-glucuronyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Podosome Cytoplasm Cytosol Early Endosome Membrane Cell Projection Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynapse Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Golgi Membrane Extracellular Region Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein C-terminus Binding Lipid Binding SH3 Domain Binding Phosphatase Binding Beta-1 Adrenergic Receptor Binding Identical Protein Binding Ion Channel Binding Cadherin Binding GTPase Binding	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Metal Ion Binding
	Biological Process	Signal Transduction Central Nervous System Development Synaptic Vesicle Uncoating Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Endocytosis	Carbohydrate Metabolic Process Protein Glycosylation Glycosaminoglycan Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Cellular Response To Hypoxia
Pathways		EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell	A tetrasaccharide linker sequence is required for GAG synthesis
Drugs			D-tartaric acid Uridine-5'-Diphosphate
Diseases
GWAS		Hematocrit ( 32888494) Red cell distribution width ( 32888494)	N-glycan levels ( 21908519) Prostate cancer ( 29892016) Verbal declarative memory ( 25648963)
Interacting Genes		37 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PRR5-ARHGAP8 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 SYNJ1 VIM VPS37C YWHAZ	3 interacting genes: CMTM7 HLA-DMA SH3GL1
Entrez ID		6455	27087
HPRD ID		03462	06969
Ensembl ID		ENSG00000141985	ENSG00000109956
Uniprot IDs		Q6FGM0 Q99961	Q9P2W7
PDB IDs			1V82 1V83 1V84
Enriched GO Terms of Interacting Partners?
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