SGK1 and PPP2CA

SGK1

PPP2CA

Description serum/glucocorticoid regulated kinase 1 protein phosphatase 2 catalytic subunit alpha
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blond vs. brown/black hair color ( 30531825)
  • Body mass index (smoking years interaction) ( 23192594)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
  • Pelvic organ prolapse ( 26545240)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Refractive error ( 32231278)
  • Schizophrenia (inflammation and infection response interaction) ( 25781172)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 37 interacting genes: ASPG BRAF CAMKK1 CARHSP1 CDKN1B CETN3 CREB1 FANCA FOXO3 GADD45G GSK3A GSK3B IKBKG KCNJ1 KPNA2 MAGEA1 MAL2 MAPK7 MAPKAP1 MLLT3 NDRG1 NDRG4 NEDD4 NEDD4L NEK6 PDK1 PDK2 PDPK1 PIK3CA PIN1 PPP2CA RABAC1 RICTOR SLC1A3 SLC9A3R2 TMEM184C UBC 96 interacting genes: ADCY8 AKAP6 AKT1 AKT3 AMOTL2 APC AXIN1 BCL2 BEST1 BMPR1B BRAF C3orf36 CAD CAMK1 CARD11 CAV1 CCNG1 CCNG2 CDC42BPB CDK2 CDK6 CDKN2C CEBPA CHEK2 CLPP CSNK2B CXCR2 DELEC1 DVL3 EEF2 EIF4EBP1 ETF1 FCAR GABRB3 GAD1 GOLGA2 HTT IGBP1 ISYNA1 JAK2 KISS1R L3MBTL3 MAPK1 MAPK3 MAPT MID1 MRPS26 MYC MYH9 NME2 NOSIP NXN PACS1 PAK1 PIM1 PPP1CA PPP2R1A PPP2R1B PPP2R2A PPP2R3B PPP2R5B PPP2R5C PPP2R5E PRKAA1 PRKCD PTEN PTN PXN PYGM RACGAP1 RBL2 RELA RHO RHOB RORC RPS6KB1 RRAS SET SGK1 SGO1 SGO2 STAT5A STAT5B STRN TIAM1 TLX1 TP53 TRIM28 TRIM35 TRIP13 TSC2 UBAP2 VAC14 VDR XRN1 YPEL3
Entrez ID 6446 5515
HPRD ID 04264 08912
Ensembl ID ENSG00000118515 ENSG00000113575
Uniprot IDs B7Z325 E9PR89 O00141 B3KUN1 P67775
PDB IDs 2R5T 3HDM 3HDN 2IAE 2IE3 2IE4 2NPP 2NYL 2NYM 3C5W 3DW8 3FGA 3K7V 3K7W 3P71 4I5L 4I5N 4IYP 4LAC 5W0W 6NTS
Enriched GO Terms of Interacting Partners?
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