SET and REPIN1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SET	REPIN1
Description		SET nuclear proto-oncogene	replication initiator 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleoplasm Nuclear Origin Of Replication Recognition Complex Chromosome
	Molecular Function	DNA Binding Chromatin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Histone Binding	DNA Binding RNA Binding Chromatin Insulator Sequence Binding Metal Ion Binding
	Biological Process	DNA Replication Nucleosome Assembly Nucleosome Disassembly Viral Process Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Histone Acetylation Regulation Of MRNA Stability Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated	DNA Replication Regulation Of Transcription By RNA Polymerase II
Pathways		Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457)	Circulating chemerin levels ( 25521368)
Interacting Genes		68 interacting genes: ANP32A APEX1 APP CALM1 CDCA8 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 ENO1 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H1-1 H2BC1 H3-3A H3-4 H4-16 H4C14 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PAX6 PIK3CG PPP2CA PPP2R1B PRKAR1A PTEN PTMA RAC1 REPIN1 SDCBP SETBP1 SGO1 SGO2 TAF1A TERF1 TERF2 TERF2IP TEX35 THAP7 TLE5 TREX1 TRIM55 TRIM63 UCHL5 XRCC6 ZNF17 ZNF438 ZNF85	4 interacting genes: GATA3 GMNN HDAC1 SET
Entrez ID		6418	29803
HPRD ID		09023	17966
Ensembl ID		ENSG00000119335	ENSG00000214022
Uniprot IDs		A0A024R895 A0A0C4DFV9 Q01105 Q5VXV3	A0A090N8H1 Q9BWE0
PDB IDs		2E50
Enriched GO Terms of Interacting Partners?
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