TMBIM1 and TMEM242

Data Source:
BioGRID (two hybrid)

		TMBIM1	TMEM242
Description		transmembrane BAX inhibitor motif containing 1	transmembrane protein 242
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Golgi Apparatus Plasma Membrane Endosome Membrane Integral Component Of Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Death Receptor Binding Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Catalytic Activity Neutrophil Degranulation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Fas Signaling Pathway Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Blood Vessel Remodeling
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Gallstone disease ( 30504769) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Red cell distribution width ( 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)
Interacting Genes		13 interacting genes: B3GALNT2 BIK CD33 F2RL1 GGT6 PROK2 RCHY1 RIC3 SLC10A1 SOCS5 TMEM242 TRIM55 TRIM63	36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1
Entrez ID		64114	729515
HPRD ID		17884
Ensembl ID		ENSG00000135926	ENSG00000215712
Uniprot IDs		A0A024R472 B3KSM0 B4DUD2 Q969X1	Q9NWH2
PDB IDs
Enriched GO Terms of Interacting Partners?
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