TMEM242 and MFSD2A

Data Source:
BioGRID (two hybrid)

		TMEM242	MFSD2A
Description		transmembrane protein 242	major facilitator superfamily domain containing 2A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Transporter Activity Long-chain Fatty Acid Transporter Activity Phospholipid Transporter Activity Fatty Acid Transmembrane Transporter Activity Symporter Activity Lysophospholipid:sodium Symporter Activity Lysophosphatidylcholine Flippase Activity Oleate Transmembrane Transporter Activity
	Biological Process		Retinal Pigment Epithelium Development Phosphatidylcholine Biosynthetic Process Brain Development Photoreceptor Cell Morphogenesis Carbohydrate Transport Cellular Response To Starvation Positive Regulation Of Triglyceride Biosynthetic Process Organic Anion Transport Fatty Acid Transport Long-chain Fatty Acid Transport Hippocampus Development Positive Regulation Of Cell Growth Negative Regulation Of Fatty Acid Beta-oxidation Very-low-density Lipoprotein Particle Assembly Maintenance Of Blood-brain Barrier Photoreceptor Cell Outer Segment Organization Regulation Of Multicellular Organism Growth Transcytosis Regulation Of Dendrite Development Cognition Lysophospholipid Transport Transmembrane Transport Retina Morphogenesis In Camera-type Eye Establishment Of Blood-brain Barrier Motor Behavior Organic Substance Transport Energy Homeostasis Lysophospholipid Translocation Regulation Of Neuron Projection Arborization Transport Across Blood-brain Barrier Regulation Of Phosphatidylcholine Metabolic Process Regulation Of Phosphatidylethanolamine Metabolic Process Regulation Of Phosphatidylserine Metabolic Process Lipid Transport Across Blood-brain Barrier Embryonic Brain Development Establishment Of Blood-retinal Barrier
Pathways			Synthesis of PC
Drugs
Diseases
GWAS		Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean platelet volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 28957414) Refractive error ( 32231278) Time to smoke first cigarette in the morning ( 31294817) Triglyceride levels ( 32203549)
Interacting Genes		36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1	2 interacting genes: ADRB2 TMEM242
Entrez ID		729515	84879
HPRD ID			07861
Ensembl ID		ENSG00000215712	ENSG00000168389
Uniprot IDs		Q9NWH2	B4DNN7 E7EPI8 Q71RE4 Q8NA29
PDB IDs
Enriched GO Terms of Interacting Partners?
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