RSPO4 and ZNF77

Data Source:
BioGRID (two hybrid)

		RSPO4	ZNF77
Description		R-spondin 4	zinc finger protein 77
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Nucleus
	Molecular Function	Protein Binding Heparin Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Molecular_function Protein Binding Metal Ion Binding
	Biological Process	Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Nail Development	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways		Regulation of FZD by ubiquitination	Generic Transcription Pathway
Drugs
Diseases		Anonychia congenita
GWAS		Blood protein levels ( 30072576) Lean body mass ( 28552196) Logical memory (immediate recall) in Alzheimer's disease dementia ( 29274321)	Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Daytime sleep phenotypes ( 27126917) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566)
Interacting Genes		15 interacting genes: ANKRD11 DHX57 GNG13 GPSM3 GUCD1 HGS KLHL38 LGR4 MAPK9 MKRN3 PIH1D2 STK16 USP20 ZNF330 ZNF77	7 interacting genes: FTO MBD3L1 METTL27 NICN1 PRDX3 RSPO4 RUSC1
Entrez ID		343637	58492
HPRD ID		18788	08936
Ensembl ID		ENSG00000101282	ENSG00000175691
Uniprot IDs		Q2I0M5	Q15935
PDB IDs
Enriched GO Terms of Interacting Partners?
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