RTN1 and DRD2

  • Data Source:
  • BioGRID (two hybrid)

RTN1

DRD2

Description reticulon 1 dopamine receptor D2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Broad depression or schizophrenia ( 30626913)
  • Putamen volume ( 31530798)
  • Schizophrenia ( 30285260)
  • Alcohol consumption ( 31358974)
  • Alcohol consumption (drinks per week) ( 30643258 30679032)
  • Alcohol consumption (heavy vs. light/non-drinkers) ( 31998841)
  • Alcohol use disorder ( 30940813)
  • Alcoholic chronic pancreatitis ( 28754779)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 26426971)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • General factor of neuroticism ( 30867560)
  • Inferior temporal gyrus volume ( 31530798)
  • Information processing speed ( 25869804)
  • Interferon alpha levels in systemic lupus erythematosus ( 25338677)
  • Mood instability ( 31168069)
  • Neuroticism ( 27089181 29255261)
  • Problematic alcohol use ( 32451486)
  • Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Select biomarker traits ( 17903293)
  • Sleep duration ( 27992416)
  • Systolic blood pressure in sickle cell anemia ( 24058526)
  • Triglycerides ( 30275531)
Interacting Genes 15 interacting genes: ADRB2 BCL2L1 CCR4 CHRM5 DRD2 F2RL1 FGFR1 FHIP1B HDAC8 LMNA NDRG1 PLEKHF2 SDCBP SPAST UGCG 82 interacting genes: ABCA2 ADGRB1 ADGRG1 ADORA2A APH1A ARL1 ARL6IP6 ATP6V0A2 ATP6V0C BCAP29 BCAP31 CADPS CADPS2 CALM1 CALM3 CCKBR CERS1 CERS2 CHPT1 CLDND1 CLIC6 CRELD1 EPB41 EPB41L1 FLNA GABBR1 GABBR2 GDPD2 GHITM GIPC1 GNAI2 GNAI3 GNAZ GNB5 GPR137 GPR37 GRIA2 GRINA KCNJ6 KCNJ9 LPAR1 NCS1 NDUFV1 NEFM NSF PAQR6 PAWR PIGG PLLP PLPPR3 PPP1R9B RHBDD2 RTN1 RTN3 RTN4 SERINC3 SLC15A4 SLC22A17 SLC35B1 SLC4A3 SLC6A1 SLC6A3 SMIM7 SPP1 SSTR2 SSTR5 SYNGR2 TF TMEFF2 TMEM101 TMEM11 TMEM63A TRAM1 TRPC4 TRPC5 TSPAN3 TSPAN7 TTYH1 WFS1 WLS YIPF3 ZDHHC4
Entrez ID 6252 1813
HPRD ID 02921 00539
Ensembl ID ENSG00000139970 ENSG00000149295
Uniprot IDs A8K3B9 Q16799 A0A024R3C5 A0A024R3I6 P14416
PDB IDs 1I15 5AER 6CM4 6LUQ 6VMS
Enriched GO Terms of Interacting Partners?
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