CLIP1 and MAPRE2

Data Source:
HPRD (in vitro)

		CLIP1	MAPRE2
Description		CAP-Gly domain containing linker protein 1	microtubule associated protein RP/EB family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Ruffle Nucleus Cytoplasm Centrosome Cytosol Microtubule Intermediate Filament Microtubule Cytoskeleton Cytoplasmic Vesicle Membrane Microtubule Plus-end Macropinosome	Cytoplasm Microtubule Organizing Center Cytoplasmic Microtubule Focal Adhesion Microtubule Cytoskeleton Microtubule Plus-end Spindle Midzone
	Molecular Function	Protein Binding Microtubule Binding Zinc Ion Binding Tubulin Binding Microtubule Plus-end Binding	Protein Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Mitotic Cell Cycle Microtubule Bundle Formation Positive Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization	Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity Spindle Assembly Cell Division Positive Regulation Of Keratinocyte Migration Positive Regulation Of Focal Adhesion Disassembly Protein Localization To Microtubule Plus-end
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases activate IQGAPs RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Adiponectin levels ( 31178129) Body mass index ( 26961502 25673413) Chronotype ( 30696823) Hip circumference ( 25673412) Weight ( 28552196)	Cerebrospinal fluid AB1-42 levels ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial morphology ( 29921221) Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: BIN1 CALM1 CLASP2 CLIP4 DCTN1 IQGAP1 MAPRE2 MTOR PAFAH1B1 REL TSC22D2 TUBA1A TUBB	28 interacting genes: APC APP AURKA AURKB CASK CDK2 CDK4 CLASP2 CLIP1 CRTAC1 DDIT4L FBXO7 GAS2L2 GTSE1 LMNA LMO2 LNX1 MAPRE1 MAPRE3 NIF3L1 PAXIP1 RBM10 RBM6 SLAIN2 TRAF1 TRAIP TXN2 UBC
Entrez ID		6249	10982
HPRD ID		01568	16157
Ensembl ID		ENSG00000130779	ENSG00000166974
Uniprot IDs		A0A024RBR1 B3KXA5 P30622	A0A024RC33 Q15555
PDB IDs		2CP5 2CP6 2E3H 2E3I 2E4H 2HQH 2QK0 3E2U 3RDV
Enriched GO Terms of Interacting Partners?
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