RGS16 and GNAT1

Data Source:
HPRD (in vitro)

		RGS16	GNAT1
Description		regulator of G protein signaling 16	G protein subunit alpha transducin 1
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Intrinsic Component Of Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytosol Heterotrimeric G-protein Complex Plasma Membrane Membrane Apical Plasma Membrane Photoreceptor Connecting Cilium Photoreceptor Outer Segment Membrane Neuronal Cell Body Photoreceptor Disc Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding Calmodulin Binding	Acyl Binding G Protein-coupled Receptor Binding GTPase Activity GTP Binding GDP Binding Protein Kinase Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste G Protein-coupled Adenosine Receptor Signaling Pathway Protein Folding Signal Transduction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction, Visible Light Cell Population Proliferation Response To Light Stimulus Response To Light Intensity Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Eye Photoreceptor Cell Development Detection Of Light Stimulus Involved In Visual Perception Sensory Perception Of Umami Taste Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events	PLC beta mediated events PLC beta mediated events G-protein activation Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs			Cacodylic acid Guanosine-5'-Diphosphate Tetrafluoroaluminate Ion
Diseases			Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS		Chronotype ( 26955885 30696823 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416)	Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Schizophrenia ( 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: CREB3L2 CSK EGFR GDE1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAT1 LYN SRC ST14	3 interacting genes: F2R RGS16 RGS9
Entrez ID		6004	2779
HPRD ID		03945	08850
Ensembl ID		ENSG00000143333	ENSG00000114349
Uniprot IDs		O15492	A1LQ23 P11488
PDB IDs		2BT2 2IK8	3RBQ
Enriched GO Terms of Interacting Partners?
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