REV3L and REV1

Data Source:
HPRD (two hybrid)

		REV3L	REV1
Description		REV3 like, DNA directed polymerase zeta catalytic subunit	REV1 DNA directed polymerase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Zeta DNA Polymerase Complex	Nucleoplasm
	Molecular Function	Nucleotide Binding DNA Binding DNA-directed DNA Polymerase Activity Protein Binding 3'-5' Exonuclease Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding	Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity Metal Ion Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA-dependent DNA Replication Error-prone Translesion Synthesis Nucleic Acid Phosphodiester Bond Hydrolysis	DNA Replication Response To UV Translesion Synthesis Error-prone Translesion Synthesis Error-free Translesion Synthesis
Pathways		Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI	Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 26414677) Psoriasis ( 25574825) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 32203549) Ulcerative colitis ( 28067908)	Bipolar disorder ( 21926972)
Interacting Genes		5 interacting genes: CHEK2 HDAC4 MAD2L1 MAD2L2 REV1	13 interacting genes: CLK1 FAAP20 FHL2 MAD2L2 POLD3 POLDIP2 POLH POLI POLK POLL REV3L TSC22D2 UBC
Entrez ID		5980	51455
HPRD ID		04145	16202
Ensembl ID		ENSG00000009413	ENSG00000135945
Uniprot IDs		O60673 Q9UG47	Q49AI5 Q9UBZ9
PDB IDs		3ABD 3ABE 3VU7 4EXT 4GK0 4GK5 5O8K 6BC8 6BCD 6BI7 6EKM 6KEA	2EBW 2LSI 2LSK 2LSY 2N1G 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5 5VZM 6ASR 6AXD
Enriched GO Terms of Interacting Partners?
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