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REV1 and MAD2L2
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
REV1
MAD2L2
Description
REV1 DNA directed polymerase
mitotic arrest deficient 2 like 2
Image
GO Annotations
Cellular Component
Nucleoplasm
Nucleus
Nucleoplasm
Anaphase-promoting Complex
Chromosome
Nucleolus
Spindle
Cytosol
Zeta DNA Polymerase Complex
Site Of Double-strand Break
Molecular Function
Damaged DNA Binding
DNA-directed DNA Polymerase Activity
Protein Binding
Deoxycytidyl Transferase Activity
Metal Ion Binding
RNA Polymerase II Activating Transcription Factor Binding
Protein Binding
JUN Kinase Binding
Biological Process
DNA Replication
Response To UV
Translesion Synthesis
Error-prone Translesion Synthesis
Error-free Translesion Synthesis
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Double-strand Break Repair
Actin Filament Organization
Mitotic Spindle Assembly Checkpoint
Negative Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Transcription By Competitive Promoter Binding
Positive Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Protein Catabolic Process
Error-prone Translesion Synthesis
DNA Damage Response, Signal Transduction Resulting In Transcription
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Isotype Switching
Positive Regulation Of Transcription, DNA-templated
Cell Division
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Ubiquitin Protein Ligase Activity
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
Negative Regulation Of Transcription Regulatory Region DNA Binding
Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Translesion synthesis by REV1
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
Translesion synthesis by REV1
Translesion synthesis by POLK
Translesion synthesis by POLI
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Arterial stiffness (brachial-femoral pulse wave velocity) (
32790701
)
Visceral adipose tissue adjusted for BMI (
22589738
)
Interacting Genes
13 interacting genes:
CLK1
FAAP20
FHL2
MAD2L2
POLD3
POLDIP2
POLH
POLI
POLK
POLL
REV3L
TSC22D2
UBC
47 interacting genes:
ADAM15
ADAM17
ADAM9
C20orf85
CAMK2B
CDC20
CDH1
DEPDC5
ELK1
FAM217B
FTO
FZR1
GSC2
IKZF1
IKZF3
INCA1
KCTD9
KRT34
MAD2L1
MAD2L1BP
MBD3L1
MYBPC2
PLAGL2
POLDIP2
PPM1B
PRCC
PRR5L
PRRC2A
RAB11FIP4
RBBP6
REL
REV1
REV3L
SFI1
SHLD1
TCF4
THAP6
TRIM27
TRIM54
TRIM7
YPEL3
YY1AP1
ZBED1
ZMYND12
ZNF511
ZNF558
ZNF655
Entrez ID
51455
10459
HPRD ID
16202
07246
Ensembl ID
ENSG00000135945
ENSG00000116670
Uniprot IDs
Q49AI5
Q9UBZ9
A0A024R4I4
Q9UI95
PDB IDs
2EBW
2LSI
2LSK
2LSY
2N1G
3GQC
3VU7
4BA9
4EXT
4GK0
4GK5
5VZM
6ASR
6AXD
3ABD
3ABE
3VU7
4EXT
4GK0
4GK5
5XPT
5XPU
6BC8
6BCD
6BI7
6K07
6K08
6KEA
6KTO
6NIF
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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