RAD52 and DCP1A

Data Source:
BioGRID (two hybrid)

		RAD52	DCP1A
Description		RAD52 homolog, DNA repair protein	decapping mRNA 1A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Protein-containing Complex Protein-DNA Complex	P-body Nucleus Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	DNA Binding Single-stranded DNA Binding Protein Binding Identical Protein Binding	MRNA Binding Protein Binding Enzyme Activator Activity Hydrolase Activity Kinesin Binding Enzyme Regulator Activity Identical Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Recombinase Assembly Double-strand Break Repair DNA Recombination Mitotic Recombination Cellular Response To DNA Damage Stimulus DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Cellular Response To Oxidative Stress Double-strand Break Repair Via Single-strand Annealing Regulation Of Nucleotide-excision Repair	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Catalytic Activity Regulation Of MRNA Stability Exonucleolytic Catabolism Of Deadenylated MRNA Protein Localization To Cytoplasmic Stress Granule
Pathways		SUMOylation of DNA damage response and repair proteins HDR through Single Strand Annealing (SSA)	mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Body mass index ( 26426971) Eosinophil percentage of granulocytes ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lung cancer ( 22899653) Neutrophil percentage of granulocytes ( 27863252) Small cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418) Youthful appearance (self-reported) ( 32339537)	Body mass index ( 26426971) Electrocardiographic traits ( 25055868) Erosive tooth wear (severe vs non-severe) ( 29898447) Heart rate ( 23583979) PR interval ( 32439900) Refractive error ( 32231278) Spontaneous preterm birth (preterm delivery) ( 25599974)
Interacting Genes		25 interacting genes: ABL1 AURKB DCP1A ERCC1 ERCC2 ERCC3 ERCC4 KPNA3 KPNA5 MCM2 MCM3 MEOX1 MEOX2 NFYC PAX5 PLK3 RAD51 RDM1 RPA1 RPA2 SEM1 SUMO1 TTK UBE2I WRN	16 interacting genes: AGO1 AGO2 DCP2 FHL2 LSM8 MAPK3 MIR15B NSMAF PAXIP1 PNRC2 RAD52 RITA1 SMAD4 TTF2 UPF1 YWHAG
Entrez ID		5893	55802
HPRD ID		11855	06113
Ensembl ID		ENSG00000002016	ENSG00000272886
Uniprot IDs		B7Z2G8 B7Z5Q6 F5GX32 P43351 Q5DR82	Q9NPI6
PDB IDs		1H2I 1KN0 5JRB 5XRZ 5XS0	2WX3 4B6H
Enriched GO Terms of Interacting Partners?
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