DCP1A and RITA1

Data Source:
BioGRID (two hybrid)

		DCP1A	RITA1
Description		decapping mRNA 1A	RBPJ interacting and tubulin associated 1
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GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule	Nucleus Nucleoplasm Cytoplasm Centrosome
	Molecular Function	MRNA Binding Protein Binding Enzyme Activator Activity Hydrolase Activity Kinesin Binding Enzyme Regulator Activity Identical Protein Binding	Protein Binding Tubulin Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Catalytic Activity Regulation Of MRNA Stability Exonucleolytic Catabolism Of Deadenylated MRNA Protein Localization To Cytoplasmic Stress Granule	Negative Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Neurogenesis Negative Regulation Of Notch Signaling Pathway Nuclear Export
Pathways		mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiographic traits ( 25055868) Erosive tooth wear (severe vs non-severe) ( 29898447) Heart rate ( 23583979) PR interval ( 32439900) Refractive error ( 32231278) Spontaneous preterm birth (preterm delivery) ( 25599974)
Interacting Genes		16 interacting genes: AGO1 AGO2 DCP2 FHL2 LSM8 MAPK3 MIR15B NSMAF PAXIP1 PNRC2 RAD52 RITA1 SMAD4 TTF2 UPF1 YWHAG	4 interacting genes: APP DCP1A GOLGA2 HOOK2
Entrez ID		55802	84934
HPRD ID		06113	08606
Ensembl ID		ENSG00000272886	ENSG00000139405
Uniprot IDs		Q9NPI6	A0A024RBL1 Q96K30
PDB IDs		2WX3 4B6H	5EG6
Enriched GO Terms of Interacting Partners?
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