RAD23B and USP25

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RAD23B	USP25
Description		RAD23 homolog B, nucleotide excision repair protein	ubiquitin specific peptidase 25
Image
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytosol XPC Complex	Nucleus Endoplasmic Reticulum Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity Ubiquitin-like Protein-specific Protease Activity Ubiquitin Protein Ligase Binding SUMO Binding Ubiquitin Binding ATPase Binding
	Biological Process	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Protein Folding Spermatogenesis Protein Deubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Global Genome Nucleotide-excision Repair Cellular Response To Interleukin-7	Cellular Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of ERAD Pathway
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER	Ub-specific processing proteases
Drugs
Diseases
GWAS		Body mass index ( 20966902) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)	Crohn's disease ( 25489960) Metabolite levels ( 23823483) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Panic disorder ( 19165232) Parkinson's disease ( 21738487) QRS complex (12-leadsum) ( 27659466) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		30 interacting genes: ADRM1 ATXN3 CALM1 DBI DEAF1 HIP1 HMGB1 MKRN1 MLH1 MPG NGLY1 PAQR3 PAX3 PNMA5 POU6F2 PSMC2 PSMD4 PUF60 RPA1 RSC1A1 TAX1BP1 TDG UBA2 UBB UBC UBE3A UBQLN2 USP25 XPC ZFAND5	21 interacting genes: ACTA1 FBXL17 FLNC GAPDH MAGEB4 MID2 MT2A PUS10 RAD23A RAD23B SENP1 SKIL SUMO1 SUMO2 SUMO3 SYK TMEM43 TNKS UBC UBE2I ZNF426
Entrez ID		5887	29761
HPRD ID		06772	05296
Ensembl ID		ENSG00000119318	ENSG00000155313
Uniprot IDs		B7Z4W4 P54727	Q9UHP3
PDB IDs		1P1A 1PVE 1UEL	2MUX 5GP7 5O71 6H4J 6H4K 6HEL 6HEM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?