RAC3 and NRBP1

Data Source:
HPRD (in vitro)

		RAC3	NRBP1
Description		Rac family small GTPase 3	nuclear receptor binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endomembrane System Lamellipodium Growth Cone Cytoplasmic Vesicle Filamentous Actin Cell Projection Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery	Nucleoplasm Cytoplasm Cell Cortex Endomembrane System Membrane Lamellipodium
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Calcium-dependent Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Regulation Of Neuron Maturation Wnt Signaling Pathway Cerebral Cortex GABAergic Interneuron Development Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Homeostasis Of Number Of Cells Within A Tissue Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Synaptic Transmission, GABAergic Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Signal Transduction
Pathways		Rho GTPase cycle PCP/CE pathway	Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Bone mineral density (total hip) ( 29883787) Creatinine levels ( 31015462) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Takayasu arteritis ( 25604533)
Interacting Genes		10 interacting genes: ANKRD11 AR ARFIP2 ARHGDIA ARHGDIB CIB1 ESR1 HDAC7 HNF1A NRBP1	14 interacting genes: C2orf50 CDKN1A CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 SNX31 SORBS3 TK1 TSC22D4
Entrez ID		5881	29959
HPRD ID		03629	05819
Ensembl ID		ENSG00000169750	ENSG00000115216
Uniprot IDs		P60763	F8W6G1 Q9UHY1
PDB IDs		2C2H 2G0N 2IC5 2OV2 2QME 6TM1
Enriched GO Terms of Interacting Partners?
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