NRBP1 and RAC3

Data Source:
HPRD (in vitro)

		NRBP1	RAC3
Description		nuclear receptor binding protein 1	Rac family small GTPase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cell Cortex Endomembrane System Membrane Lamellipodium	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endomembrane System Lamellipodium Growth Cone Cytoplasmic Vesicle Filamentous Actin Cell Projection Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Calcium-dependent Protein Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Signal Transduction	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Regulation Of Neuron Maturation Wnt Signaling Pathway Cerebral Cortex GABAergic Interneuron Development Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Homeostasis Of Number Of Cells Within A Tissue Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Synaptic Transmission, GABAergic Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		Nuclear Receptor transcription pathway	Rho GTPase cycle PCP/CE pathway
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787) Creatinine levels ( 31015462) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Takayasu arteritis ( 25604533)	Refractive error ( 32231278)
Interacting Genes		14 interacting genes: C2orf50 CDKN1A CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 SNX31 SORBS3 TK1 TSC22D4	10 interacting genes: ANKRD11 AR ARFIP2 ARHGDIA ARHGDIB CIB1 ESR1 HDAC7 HNF1A NRBP1
Entrez ID		29959	5881
HPRD ID		05819	03629
Ensembl ID		ENSG00000115216	ENSG00000169750
Uniprot IDs		F8W6G1 Q9UHY1	P60763
PDB IDs			2C2H 2G0N 2IC5 2OV2 2QME 6TM1
Enriched GO Terms of Interacting Partners?
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