RAC3 and ANKRD11

Data Source:
HPRD (two hybrid, in vitro)

		RAC3	ANKRD11
Description		Rac family small GTPase 3	ankyrin repeat domain 11
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endomembrane System Lamellipodium Growth Cone Cytoplasmic Vesicle Filamentous Actin Cell Projection Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery	Nucleus Nucleoplasm Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Calcium-dependent Protein Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Regulation Of Neuron Maturation Wnt Signaling Pathway Cerebral Cortex GABAergic Interneuron Development Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Homeostasis Of Number Of Cells Within A Tissue Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Synaptic Transmission, GABAergic Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	Anatomical Structure Morphogenesis Odontogenesis Of Dentin-containing Tooth Skeletal System Morphogenesis Face Morphogenesis
Pathways		Rho GTPase cycle PCP/CE pathway
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Eosinophil counts ( 32888494) Hemoglobin levels ( 32327693) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 32888494)
Interacting Genes		10 interacting genes: ANKRD11 AR ARFIP2 ARHGDIA ARHGDIB CIB1 ESR1 HDAC7 HNF1A NRBP1	93 interacting genes: ABHD11 AGR2 ANKRD33 ARID3A ARID5A BHLHB9 BRCC3 C10orf82 C11orf1 C18orf54 C1QTNF2 CALCA CCDC196 CCHCR1 CCN3 CDC23 CDCA7L CDR2L CEP44 COG4 DEPTOR FAM136A FAM221B FOLR3 FTO GOLGA2 GOLGA6L9 GRIPAP1 HAUS3 HDAC3 HDAC4 HDAC5 HOMEZ HOOK2 HRAS IGFBP6 IKZF1 ITGB3BP KANK2 KPNA3 KPNA6 KRT34 LZTS2 MKRN3 MTFR1L MTUS2 MXRA8 MYF5 NAB2 NCOA1 NCOA2 NCOA3 NOTO NTAQ1 PDE4DIP PIH1D2 PLAGL2 PPARA RAC3 RCOR3 RINT1 RPH3AL RSPO4 RUBCN SERTAD3 SNRNP35 SPANXN2 SPATA2 SPRY1 SRC STMN3 STRA8 SYTL3 TADA2B TFIP11 TLE5 TNNI1 TRAF2 TRIM37 TRIM54 TSPOAP1 TTC23L TXN UFC1 USH1G USP54 USP6 VDR ZNF426 ZNF552 ZNF655 ZNF688 ZRANB1
Entrez ID		5881	29123
HPRD ID		03629	12456
Ensembl ID		ENSG00000169750	ENSG00000167522
Uniprot IDs		P60763	Q6UB99
PDB IDs		2C2H 2G0N 2IC5 2OV2 2QME 6TM1
Enriched GO Terms of Interacting Partners?
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