RAD1 and RHNO1

Data Source:
BioGRID (pull down)

		RAD1	RHNO1
Description		RAD1 checkpoint DNA exonuclease	RAD9-HUS1-RAD1 interacting nuclear orphan 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Checkpoint Clamp Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Chromosome
	Molecular Function	Damaged DNA Binding Protein Binding 3'-5' Exonuclease Activity Exodeoxyribonuclease III Activity	Protein Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair Cellular Response To DNA Damage Stimulus Substantia Nigra Development Meiotic Recombination Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Signal Transduction By P53 Class Mediator	DNA Damage Checkpoint Recombinational Repair DNA Replication Cell Cycle Cellular Response To UV Positive Regulation Of G0 To G1 Transition Cellular Response To Ionizing Radiation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint	HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		24 interacting genes: COPS5 CSNK2A1 CSNK2A2 DNAJC7 FEN1 HUS1 HUS1B MAP1LC3B MSH2 MSH3 MSH6 NEIL1 OGG1 POLB PRKN RAD17 RAD9B RHNO1 RPA1 RPA2 SIRT6 TDG TOPBP1 WRN	12 interacting genes: BANP CYSRT1 GOLGA2 HUS1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LZTS2 RAD1 RAD9A TFIP11 TOPBP1
Entrez ID		5810	83695
HPRD ID		04400	17487
Ensembl ID		ENSG00000113456	ENSG00000171792
Uniprot IDs		A0A024R045 O60671	Q9BSD3
PDB IDs		3A1J 3G65 3GGR 6J8Y	6J8Y
Enriched GO Terms of Interacting Partners?
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